How Does It Works?
Glimepiride functions by causing the pancreatic beta cells to excrete more insulin. Naturally secreted insulin brings down the levels of glucose in the blood very effectively. Metformin has three modes of action: it suppresses the liver’s sugar production, inhibits the intestines’ sugar absorption, and enhances the body’s insulin sensitivity. Consequently, the body can metabolise dissolved sugar more efficiently. These drugs taken together offer a broad-spectrum strategy for controlling the levels of blood sugar, thus maintaining them in the desirable region.
Glimepiride + Metformin Tablet Uses
The comprehensive uses of Glimepiride 2 mg + Metformin 500 mg HCL prolonged release tablets are as follows:
- Controls Blood Sugar: Effectively reduces the high levels of glucose in the blood of Type 2 Diabetes patients.
- Increases Insulin Sensitivity: The body is able to use its insulin in a more effective way.
- Prevents Complications: The probability of suffering from long-term ailments such as kidney malfunction, nerve damage, and losing eyesight is greatly reduced.
- Cardiovascular Protection: The benefits of a well-controlled blood sugar level include a decrease in the chances of suffering from a heart attack or stroke.
- Post-Meal Spikes Management: The product prevents sudden increases in blood sugar levels that occur with the ingestion of food.
Dosage and Administration
The standard use of the medicinal tablet is that one tablet should be taken per day, ideally together with breakfast or the first main meal of the day. Take the tablet whole with a glass of water; do not chew, crush, or cut it, because this can interfere with the extended-release mechanism. Closely follow your physician’s instructions concerning the amount and period of time to take it. Do not discontinue the drug use suddenly, as this might lead to a rapid increase in blood glucose levels.
Precautions To Be Taken
You must adhere to your doctor’s instructions on medication intake and continue with your schedule. It should be taken with food always to prevent stomach upset and also to lower the chances of having low blood sugar. Do not drink alcohol when taking this medicine, because it can lead to the risk of lactic acidosis and severe hypoglycemia. Always have sugar (for example, candy or juice) in your possession in case you experience dizziness or shakiness. If you are pregnant, plan to get pregnant, or are breastfeeding, talk to your doctor about the use of this medicine first.
Potential Side Effects of Glimepiride and Metformin Tablets
As is the case with all drugs, this tablet can also produce some adverse effects, but not all users may go through it. Among the common side effects are nausea, diarrhoea, abdominal pain, and a metallic taste in the mouth. One of the common side effects that could happen but is still controllable is hypoglycemia (low blood sugar), which could lead to dizziness, sweating, palpitations, or shakiness. On the other hand, lactic acidosis and allergic reactions are examples of very infrequent yet severe side effects. Do not hesitate to call your doctor if you have severe stomach pain, fast breathing, or constant dizziness.
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Frequently Asked Questions
What is Glimepiride 2 mg + Metformin 500 mg PR used for?
This is a combined therapy for Type 2 Diabetes Mellitus. It is a medication used when the diet and physical activity regimen are insufficient to control the blood sugar levels in adults.
How does this combination work?
While Metformin reduces glucose production in the liver and enhances insulin sensitivity, Glimepiride causes the pancreas to release insulin altogether, thus lowering blood sugar.
Why is it called “Prolonged Release”?
Prolonged Release (PR) signifies that the drug is slowly released over a prolonged period into the body, thus maintaining stable blood sugar levels and minimising side effects.
What are the common side effects?
Low blood sugar (hypoglycemia), nausea, diarrhoea, upset stomach, and headache are the side effects that occur most often. They are mostly temporary and improve with time.
Can I take this medicine on an empty stomach?
No, it is better to take this tablet with food, ideally breakfast, to lower the possibility of experiencing stomach upset and low blood sugar.
